Peer-reviewed, PubMed-linked literature on the 25 research compounds Liv Pure supplies, organized by compound class.
✔ PubMed-linked citations ✔ In-vitro and preclinical only ✔ Research Use Only
The Research Library gathers 120 in-vitro, preclinical and review references across 25 compounds so that researchers can read the primary literature behind each reagent before designing an experiment. Each class page summarizes the established molecular target or pathway, the model systems used in the published work, and what the literature does not cover, with every citation linked to its PubMed record. Human clinical studies are excluded by design: Liv Pure supplies these compounds for laboratory research only, and the library is written for that audience.
Tissue-repair peptides are short synthetic peptides whose sequences are derived from, or identical to, endogenous fragments studied in models of wound closure, angiogenesis, extracellular-matrix remodeling and inflammation resolution. The compounds in this class (BPC-157, thymosin beta-4 fragment/TB-500, GHK-Cu and KPV) act through distinct mechanisms: nitric oxide and growth-factor-receptor signalling, G-actin sequestration and cell migration, copper-dependent modulation of gene expression, and melanocortin-related anti-inflammatory signalling, respectively. The literature is dominated by rodent injury models (tendon, skin, muscle, gastrointestinal, myocardial), ex vivo explants and cultured fibroblast, keratinocyte, endothelial and epithelial cell lines, together with mechanistic reviews.
Compounds covered: BPC-157, TB-500 (thymosin beta-4 fragment), GHK-Cu, KPV. Read the Tissue-Repair Peptides references (20 PubMed-linked citations).
Growth hormone secretagogues (GHS) are peptides studied for their interaction with the two receptor systems that regulate somatotroph GH release in preclinical models: the GHRH receptor (GHRH-R, a class B G protein-coupled receptor coupled to adenylate cyclase/cAMP) and the ghrelin receptor GHS-R1a (a class A GPCR coupled to Gq/phospholipase C and calcium signaling). The class is divided into GHRH analogs (GRF 1-29 fragments and their stabilized derivatives) and ghrelin-mimetic growth hormone-releasing peptides (GHRPs) such as ipamorelin. The foundational literature is largely in-vitro pharmacology (rat anterior pituitary membranes and dispersed pituitary cells, receptor cloning and transfected cell lines, plasma-enzyme stability assays) and animal models in rat and swine.
Compounds covered: Sermorelin, Ipamorelin, Mod GRF 1-29 (CJC-1295 without DAC). Read the GH Secretagogues references (15 PubMed-linked citations).
This class groups research compounds that are studied for their relationship to mitochondrial signaling, cellular energy-sensing pathways (AMPK, sirtuins, NAD+ homeostasis) and adipose lipid metabolism. It includes a mitochondrial-genome-encoded peptide (MOTS-c), an endogenous redox coenzyme (NAD+), a small-molecule NNMT inhibitor (5-Amino-1MQ) and a synthetic C-terminal fragment of human growth hormone (AOD-9604). The published literature is predominantly in-vitro (cultured adipocytes, myoblasts, HEK293 and HepG2 cells) and rodent work in diet-induced obesity, ovariectomy, aging and injury models, together with mechanistic reviews of NAD+ biology.
Compounds covered: MOTS-c, NAD+, 5-Amino-1MQ, AOD-9604. Read the Mitochondrial & Metabolic Peptides references (16 PubMed-linked citations).
Neuropeptides are short amino-acid chains that act as signaling molecules in the nervous system, typically through G-protein-coupled receptors or by allosteric modulation of ion-channel receptors, and many also carry immune and endocrine signaling roles. The compounds in this class span a wide range of origins: endogenous fragments and analogs of pituitary hormones (Semax, an ACTH(4-7)-Pro-Gly-Pro heptapeptide), tuftsin-derived synthetic heptapeptides (Selank), a nonapeptide originally isolated from rabbit cerebral venous blood (DSIP), a synthetic tripeptide of the Khavinson short-peptide family (Pinealon, Glu-Asp-Arg), and a 28-residue endogenous member of the secretin/glucagon superfamily (VIP). The preclinical literature is dominated by rodent behavioral and neurochemical studies, brain-region transcriptomics, hippocampal slice electrophysiology, receptor-expressing cell lines, and primary neuronal or immune-cell cultures.
Compounds covered: Semax, Selank, DSIP (delta sleep-inducing peptide), Pinealon, VIP (vasoactive intestinal peptide). Read the Neuropeptides references (25 PubMed-linked citations).
This class groups peptides and protein analogs that act as ligands for growth-factor and immunomodulatory receptor systems studied in cell culture and animal models. It spans thymic immunopeptides that modulate innate immune receptor signaling (Thymosin Alpha-1), a hypothalamic RF-amide neuropeptide fragment that activates a G protein-coupled receptor (Kisspeptin-10), and engineered analogs of insulin-like growth factor-I with reduced IGF-binding-protein affinity (IGF-1 LR3 and IGF-1 DES(1-3)). Research contexts range from receptor binding, second-messenger signaling and cytokine assays to myoblast, satellite-cell and organ-growth studies in preclinical species.
Compounds covered: Thymosin Alpha-1, Kisspeptin-10, IGF-1 LR3, IGF-1 DES(1-3). Read the Growth Factors & Immunopeptides references (19 PubMed-linked citations).
This class groups short synthetic peptides studied in cellular-senescence and telomere-biology models. Two distinct research threads are represented: telomere/telomerase regulation, where the tetrapeptide Epithalon has been examined in cultured human fibroblasts and other cell lines for effects on hTERT expression, telomerase activity and telomere length; and senolysis, where the cell-penetrating peptide FOXO4-DRI has been used to disrupt the FOXO4-p53 interaction and induce apoptosis selectively in senescent cells in vitro and in mouse models. The literature is predominantly preclinical (cell culture and rodent), with a substantial fraction of the Epithalon work originating from a single research group, and includes at least one animal study reporting adverse hemodynamic effects of senescent-cell clearance.
Compounds covered: Epithalon, FOXO4-DRI. Read the Senolytic & Telomere Peptides references (10 PubMed-linked citations).
This class groups small molecules and short synthetic peptides that are used in laboratory research as biochemical reagents, enzyme cofactors, or mechanistic probes rather than as receptor-targeted signaling peptides. SNAP-8 (acetyl octapeptide-3) is a synthetic N-terminal SNAP-25 mimetic peptide studied for its interaction with SNARE complex assembly; L-carnitine is the endogenous carrier molecule of the mitochondrial carnitine shuttle for long-chain fatty acids; and glutathione is the most abundant non-protein cellular thiol and the reference redox couple (GSSG/2GSH) in redox biochemistry. The research literature for these compounds is predominantly biochemical, structural, and enzymological, and is well suited to in-vitro, cell-free, and cell-culture model systems.
Compounds covered: SNAP-8 (acetyl octapeptide-3), L-Carnitine, Glutathione. Read the Reagents & Cofactors references (15 PubMed-linked citations).
All compounds referenced here are supplied for in-vitro laboratory research only and are not for human or animal use. Nothing in the Research Library is medical advice, and no statement has been evaluated by the Food and Drug Administration. Lot identity and purity are documented on each certificate of analysis.
Liv Pure supplies research-grade synthetic peptides and laboratory reagents to qualified researchers and institutions. Every lot ships with a lot-specific certificate of analysis.
Research Use Only • Lot-Specific COAs • Ships From the USA
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All products provided by Liv Pure are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration, and all products are sold strictly for research, laboratory, or analytical purposes, not for human consumption. The products offered on this site are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any disease or medical condition, and these statements have not been evaluated by the Food and Drug Administration. Liv Pure is a chemical supplier; it is not a compounding pharmacy or chemical compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under Section 503B of the Act.
