Growth hormone secretagogues (GHS) are peptides studied for their interaction with the two receptor systems that regulate somatotroph GH release in preclinical models: the GHRH receptor (GHRH-R, a class B G protein-coupled receptor coupled to adenylate cyclase/cAMP) and the ghrelin receptor GHS-R1a (a class A GPCR coupled to Gq/phospholipase C and calcium signaling). The class is divided into GHRH analogs (GRF 1-29 fragments and their stabilized derivatives) and ghrelin-mimetic growth hormone-releasing peptides (GHRPs) such as ipamorelin. The foundational literature is largely in-vitro pharmacology (rat anterior pituitary membranes and dispersed pituitary cells, receptor cloning and transfected cell lines, plasma-enzyme stability assays) and animal models in rat and swine. Later clinical work exists for several compounds but is outside the scope of this research-use-only library, which focuses on mechanism, structure-activity relationships and model systems.
Liv Pure supplies Sermorelin, Ipamorelin, and Mod GRF 1-29 (CJC-1295 without DAC) as lyophilized research reagents; each listing shows the quantities available and links to its certificate of analysis where a lot has been tested. The published in-vitro and preclinical literature for every compound in this class, with PubMed links, is collected in the GH Secretagogues section of the Research Library. All products are for in-vitro laboratory research only and are not for human or animal use.
Liv Pure supplies research-grade synthetic peptides and laboratory reagents to qualified researchers and institutions. Every lot ships with a lot-specific certificate of analysis.
Research Use Only • Lot-Specific COAs • Ships From the USA
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All products provided by Liv Pure are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration, and all products are sold strictly for research, laboratory, or analytical purposes, not for human consumption. The products offered on this site are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any disease or medical condition, and these statements have not been evaluated by the Food and Drug Administration. Liv Pure is a chemical supplier; it is not a compounding pharmacy or chemical compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under Section 503B of the Act.
