$49.99 - $119.99 $25.00 - $60.00 50% off with code LAUNCH50
For laboratory research use only. Not for human or animal use. Not for diagnostic, therapeutic, or cosmetic purposes. Supplied with a lot-specific certificate of analysis.
| Size | 10 mg, 40 mg |
|---|---|
| CAS Number | 1627580-64-6 |
| Molecular Formula | C101H152N28O22S2 |
| Molecular Weight | 2174.6 g/mol |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Form | Lyophilized powder |
| Quantity | 10 mg / 40 mg |
MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a 16-amino-acid peptide encoded within mitochondrial DNA, Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg. It is one of the small mitochondrial-derived peptides studied as signaling molecules rather than as respiratory-chain components.
Lee and colleagues identified the peptide and reported that, in cultured cells, it inhibits the folate cycle and de-novo purine biosynthesis, leading to AMPK activation, in the 2015 Cell Metabolism paper that first described MOTS-c and its cellular actions. It is used in AMPK, one-carbon-metabolism, and mitochondrial-signaling assays.
Supplied as lyophilized powder, 10 mg or 40 mg per vial. Store sealed vials at 2–8 °C for short-term holding and at −20 °C for long-term storage, protected from light and moisture.
Current certificates of analysis (PDF): 10 mg, lot 0202267 and 40 mg, lot 0202269.
For the peer-reviewed background on this compound, see the Mitochondrial and Metabolic Peptides references in the Research Library. Every tested lot’s HPLC purity result is filed on the Certificates of Analysis page, and our Testing and Quality page explains what those certificates do and do not show.
For laboratory research use only. Not for human or animal use. Not for diagnostic, therapeutic, or cosmetic purposes. Each lot ships with a certificate of analysis; match the lot number on the vial to the certificate before the material enters an assay.
Every lot Liv Pure ships is tested by an independent laboratory before release. The certificate of analysis reports chromatographic purity (HPLC) for that specific lot, and the current certificates for this compound are linked at the end of the description above, and every lot Liv Pure ships is listed on the Certificates of Analysis page. Match the lot number printed on the vial to the certificate before the material enters an assay. If a lot you hold is not listed, request its certificate from support@livpurewellness.com.
Liv Pure supplies research-grade synthetic peptides and laboratory reagents to qualified researchers and institutions. Every lot ships with a lot-specific certificate of analysis.
Research Use Only • Lot-Specific COAs • Ships From the USA
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All products provided by Liv Pure are intended solely for in-vitro laboratory research purposes. These materials are expressly forbidden for any form of human or animal use, ingestion, or administration, and all products are sold strictly for research, laboratory, or analytical purposes, not for human consumption. The products offered on this site are not formulated, designed, or intended to diagnose, cure, mitigate, treat, or prevent any disease or medical condition, and these statements have not been evaluated by the Food and Drug Administration. Liv Pure is a chemical supplier; it is not a compounding pharmacy or chemical compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under Section 503B of the Act.
